If you could look inside every single cell in your body, you would see 23 pairs of chromosomes (46 chromosomes in total). And at the end of every one of those squiggly thread-like things are telomeres. These little caps protect your genetic information from being lost when your cells divide and keep the chromosome from fusing with neighboring chromosomes.
Think of them like the ends on your shoelaces, but they’re not made of cheap plastic. They’re made from a series of DNA segments, or “base pairs,” that repeat thousands of times. In white blood cells, for example, you start out with around 8,000 base pairs at the ends of your chromosomes. Over and over again, that base-pair sequence repeats itself, almost as if you’re winding masking tape around the ends of your chromosomes to keep them snug.
But here’s the catch. When your cells divide, and they will about 50 to 70 times on average over their lifetimes, the ends of your chromosomes—well—they aren’t copied quite as perfectly as you might think. See, every time your DNA replicates itself and divides, it shaves a tiny bit (approximately 20 to 30 base pairs) off your telomeres. Oxidative stress (or the damage wrought by free radicals) messes with things as well and can cause you to lose an additional 50 to 150 base pairs per split.
That adds up and over time, telomeres shrink. And once a telomere becomes too short, it leaves your cell’s DNA exposed. That’s when a series of unwelcome biological actions can occur.
Your broken DNA might try to fix itself either by copying the sequence of another DNA molecule that’s kind of like it or by fusing together two “cap-less” chromosomes.
Neither is always a bad thing and either can temporarily do the trick. But if two chromosomes fuse, the cell can either die or become genetically abnormal. In the latter case, your abnormal cells continue to divide and become potentially dangerous.
But that’s not all. When the caps come off your chromosomes, your cells can no longer divide. Instead, they either die or become senescent cells— which are basically zombie cells that sit inside your tissues and secrete stuff (such as pro inflammatory cytokines) that damages healthier cells.
That’s why the shortening of telomeres has been associated with aging. As skin and pigment cells die, we start to see wrinkles and gray hair. But the really bad stuff is when our immune cells start to die off, and our risk of heart disease, diabetes, cognitive decline, premature death, and a number of age-related issues increases.
However, it turns out that just a few smart lifestyle choices can fortify and even lengthen your telomeres. In one study, participants switched to a diet high in fruits, vegetables, and unrefined grains; walked 30 minutes a day six days a week; and practiced stress-busting techniques such as yoga and meditation. Over time, their ...Read More
Natural Weight Loss: When you do not have actually to Go Over
Eat right, keep moving.
You just have actually read all that you need to know about how to prevent being overweight. That simple set of instructions should be easy to follow, but not for 35% of Americans who are unable to prevent being overweight.
Of course, once we are overweight, we usually want to trim down for a whole lot of reasons, some related to health, others having to do along with looks.
In addition, it is never too late to lose weight. But the fact is, it is a whole lot easier to prevent putting on pounds than to try losing them later on. And if there is one thing we all know, it is that weight gain is likely to happen if we do not take forward-looking steps to stop it.
Health experts say that most people who are into losing weight usually stray. They tend to go back to their old eating habits even after they learn to enjoy low-fat eating. They tend to return to sedentary ways despite the fact that they enjoy exercising.
But despite the energy toward weight gain, you can stop it from happening, experts say. And there are plenty of good reasons to avoid excess pounds, reasons that go beyond vanity or social acceptance.
In fact, some health experts contend that the significance of excess weight is more than cosmetic. They say that it takes a huge toll on peoples physical health.
The Way to Losing Weight Naturally
The nuts and bolts of eating right maintaining a healthy weight is not all that complicated. In fact, it is a good bet that most people know pretty well what is best. Hence, losing weight the natural way should not be a problem at all.
Consequently, a reasonable approach for losing weight naturally is to stick to a diet that is high in complex carbohydrates, high in fiber, moderate in protein, and low in fat.
A complex carbohydrate is a baked potato. Fat is the sour cream and butter you should not put on it. Fiber is vegetables. Fat is the oil you should not fry them in. Protein is a lean cut of meat. Fat is the gravy you should not pour over it.
Moreover, health experts say that dietary fat promotes weight gain because it is a very dense source of calories. Also, when you consume excess calories from dietary fat, you store those calories as body fat more efficiently than excess calories from other sources.
On the other hand, it can also help you lose weight naturally if you will not fall into the so-called fat-free trap. Manufacturers keep coming out along with low-fat or fat-free versions of their best-selling foods, but Americans keep getting fatter anyway.
One of the greatest delusions of the 1990s is that no fat means non-fattening. The truth is, you are often getting just as several calories from the no-fat version, even if the calories are not coming from fat.