A Recent Study on Obesity and Genetics in Nature Shows a Stronger Correlation Between the Two, But Calories Still Count Say Calories In, Calories Out Cookbook Authors

Bethesda, MD (PRWEB) February 18, 2015

A new study published in the journal Nature found that genetics plays a bigger role in the development of obesity than was previously thought. Researchers from the University of Michigan unveiled the results of a genome-wide association study looking at body mass index (BMI), a common measure of obesity, in close to 400,000 individuals (Nature, 518:197-206;February 11, 2015).

This new research finds that as much as 21% of BMI variation can be accounted for by genetics. There are about 100 locations across the genome that plays roles in various obesity traits, double than what was previously thought.

“This research may help determine who is at risk of developing diseases associated with obesity and may lend insight into future treatment,” says Elaine Trujillo, nutritionist and author of The Calories In Calories Out Cookbook. “We have known that one size does not fit all when it comes to weight gain, development of risk factors and even obesity treatment. Now we have more research to support that notion,” Trujillo adds.

According to Caroline Apovian, Professor of Medicine and Pediatrics and the Director of the Nutrition and Weight Management Center, Boston Medical Center, Boston University, “For those of us treating obesity, this is exciting news because particular genes and pathways affecting BMI have been implicated that respond to changes in eating behavior. Once we can figure out which of these genes are implicated in each patient, we can tailor the treatment of their obesity based on their particular genetic profile. For example, one of the pathways implicated in this paper is one that is the proposed mechanism of action of the combination of drugs recently approved by the US Food and Drug Administration for treatment of obesity – topiramate/phentermine. Based on genetic profiles, we may be able to predict which patients will be successful at weight loss with this particular drug combination (topiramate/phentermine) as opposed to another treatment if they have this pathway variation. Also, we may be able to predict who will do well with bariatric surgery in the future.”

In a companion paper on waist-to-hip circumference ratios, 49 sites in the genome were identified (Nature 518:187-186; February 12, 2015). The waist-to-hip ratio and waist circumference alone are used to determine fat distribution and abdominal fatness and is a marker for developing diseases associated with obesity. Men who have waist circumferences greater than 40 inches and women who have waist circumferences greater than 35 inches are at higher risk of diabetes, dyslipidemia, hypertension, and cardio-vascular disease.

Much more research is needed to determine how the genetic variations in individuals lead to weight gain in some and not in others. Some of the genes involved in obesity may be related to other diseases, this research is a step in uncovering the biological basis to a whole host of metabolic diseases. Although genetic background may be a useful tool in the future for developing personalized diets for weight loss and health, those ...Read More


Cooking Ideas

1200 low-fat healthy recipes for you. Order now and receive your cookbook instantly with thousands recipes for meat, soups, eggs, salads, veggie juices even low carb chocolate surprises designed specially to comply with diets. Most of the ingredients in these recipes can be bought in good health food shops, supermarkets. If you have trouble finding what you need, exchange ingredients using the carb counter provided. GOOD LUCK EAT OR WE BOTH STARVE

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Cooking Ideas

1200 low-fat healthy recipes for you. Order now and receive your cookbook instantly with thousands recipes for meat, soups, eggs, salads, veggie juices even low carb chocolate surprises designed specially to comply with diets. Most of the ingredients in these recipes can be bought in good health food shops, supermarkets. If you have trouble finding what you need, exchange ingredients using the carb counter provided. GOOD LUCK EAT OR WE BOTH STARVE

...Read More

Tips For Making A Great Sandwich

Lots of people go through their whole life convinced that they do not like sandwiches, and this is simply because they have never tasted a truly great sandwich. Sandwiches are, of course, excellent for the fact that they are easy to make and are also easy to bring with you wherever you go. Sandwiches are, of course, great for lunch and for snacks; but if you know how to make a mean sandwich, it can even be a great dinner! If you thought that there is nothing more to the sandwich than just throwing some meat on some bread, it is time for you to think again.

The most important building block of a sandwich is what you use to make it; not just desired taste, but quality as well. Although it a small amount more to purchase organic sandwich materials from a store such as Whole Foods, the extra money will be well spent. Overprocessed meat and bread does not taste nearly as fresh and as full as that meat and bread that has been organically grown and manufactured. The taste of your sandwich will also be much improved if you go with organically grown vegetables when you construct your daily masterpiece.

Sandwiches can sometimes be dry, which means that it is also important to consider what you are using to moisten your sandwich. A good sandwich will not stick to the roof of your mouth; instead, it will go down easy, so figure out what you prefer to use to help your sandwich do this, whether it is something such as mustard and mayo, or something different like salad dressing or oil and vinegar.

You also, of course, need to know how to put flavors together if your goal is to construct a truly delicious sandwich. It might seem silly to buy a sandwich cookbook, but once you delve into the treasure chest of a book such as @@AMAZONTEXT;0609610511;’wichcraft: Craft a Sandwich into a Meal–And a Meal into a Sandwich@@, you will surely understand.

Sandwiches can be a great, easy way to have some delicious food, no matter if you use them for lunch, snacks, or even for dinner; first, however, you have to learn what goes into making a sandwich great!

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